Potensi Fraksi Ekstrak Herba Krokot (Portulaca grandiflora) Varietas Bunga Magenta dalam Menyembuhkan Luka
The Magenta Flower Variety Purslane Herbs (Portulaca grandiflora) Extract Fraction Potency in Wound Healing
DOI:
https://doi.org/10.25026/jsk.v6i2.2025Abstract
Purslane rose-like flower variety (Portulaca grandiflora) is a popular decorative plant in society. Purslane utilization for health in Indonesia is still limited. Rose-like magenta flower variety purslane (P. grandiflora) is already known for its wound healing activity. This wound healing activity may occur from its secondary metabolites such as flavonoids, saponins, tannins, and terpenoids. Flavonoids extracted in a suitable solvent have the potency to increase the purslane wound healing activity. This research aimed to determine the magenta flower variety purslane herbs extract fraction potency in wound healing. This experimental research was conducted using wound-induced rabbits. The wounds were divided into negative and positive control groups, water, ethyl acetate, and n-hexane treatment groups. The wounds treated with aqua destilata re-epithelization was 12.33 ± 0.94 days, meanwhile, the wounds treated with betadine solution, water, ethyl acetate, and n-hexane fraction were 9.33 ± 0.47, 9.33 ± 0.47, 9.67 ± 0.47, dan 10.00 ± 0.00 days respectively. The water, ethyl acetate, and n-hexane fraction of magenta flower variety purslane herbs (P. grandiflora) have potency in wound healing. The water fraction showed the fastest re-epithelization pace compared to ethyl acetate and n-hexane fraction.
Keywords: fraction, purslane, Portulaca grandiflora, magenta, wound healing
Abstrak
Krokot varietas berbunga seperti mawar (Portulaca grandiflora) merupakan tanaman hias yang cukup populer di masyarakat. Di Indonesia pemanfaatan krokot untuk kesehatan masih sangat terbatas. Krokot mawar (P. grandiflora) varietas bunga magenta diketahui memiliki aktivitas penyembuhan luka. Aktivitas penyembuhan luka tersebut kemungkinan diperoleh karena kandungan metabolit sekunder seperti flavonoid, saponin, tanin, dan terpenoid. Flavonoid yang tertarik dalam pelarut yang sesuai tersebut berpotensi meningkatkan kemampuan krokot dalam menyembuhkan luka. Penelitian ini bertujuan mengetahui potensi dari fraksi ekstrak herba krokot (P. grandiflora) varietas bunga magenta dalam menyembuhkan luka. Penelitian eksperimental ini dilakukan menggunakan kelinci yang diinduksi luka pada bagian punggung. Luka dibagi menjadi kelompok kontrol negatif dan positif serta kelompok perlakuan fraksi air, etil asetat, dan n-heksana. Kelompok luka yang diberi aqua destilata menunjukkan re-epitelisasi 12.33 ± 0.94 hari, sedangkan kelompok luka yang diberi betadine solution, fraksi air, etil asetat, dan n-heksana berturut-turut 9.33 ± 0.47, 9.33 ± 0.47, 9.67 ± 0.47, dan 10.00 ± 0.00 hari. Fraksi air, etil asetat, dan n-heksana herba krokot (P. grandiflora) memiliki potensi menyembuhkan luka dengan mempercepat laju re-epitelisasi. Fraksi air menunjukkan laju re-epitelisasi yang paling baik dibandingkan fraksi etil asetat dan n-heksana.
Kata Kunci: fraksi, krokot, Portulaca grandiflora, magenta, penyembuhan luka
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